Anionic phospholipids and protein translocation
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چکیده
منابع مشابه
Inositol phospholipids: Translocation, translocation, translocation …
The pleckstrin homology (PH) domains of a number of proteins have been found to interact in vitro with inositol phospholipids; recent experiments show that these interactions may be important in directing protein translocation to specific parts of the cell following stimulus-induced lipid breakdown or synthesis.
متن کاملAnionic phospholipids are determinants of membrane protein topology.
The orientation of many membrane proteins is determined by the asymmetric distribution of positively charged amino acid residues in cytoplasmic and translocated loops. The positive-inside rule states that loops with large amounts of these residues tend to have cytoplasmic locations. Orientations of constructs derived from the inner membrane protein leader peptidase from Escherichia coli were fo...
متن کاملRetinoschisin is a peripheral membrane protein with affinity for anionic phospholipids and affected by divalent cations.
PURPOSE Retinoschisin (RS) is a retina-specific, secreted protein implicated in X-linked juvenile retinoschisis and essential for the structural and functional integrity of the retina. This biochemical characterization and ultrastructural localization of RS in intact murine retina was performed to further understanding of the molecular basis of its function. METHODS Subcellular fractions and ...
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Spectrin, previously identified as one of the major proteins of the mammalian erythrocyte skeleton, was discovered in most animal cells. Brain spectrin, also known as fodrin, is one of the best studied nonerythroid proteins of the spectrin family. Erytrocyte spectrin can interact with the lipid domains in natural membranes and in model systems. We have found, that brain spectrin interacts with ...
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Assrnann, G. (1994) J. Biol. Chern. 269, 21277-21283 19 Wanders, R. J. A., Denis, S., Wouters, F., Wirtz, K. W. A. and Seedorf, U. (1997) Biochern. Biophys. Res. Cornrnun. 236,565-567 20 Antonenkov, V. D., van Veldhoven, P. P., Waelkens, E. and Mannaerts, G. P. (1997) J. Biol. Chern. 272, 26023-2603 1 21 Ossendorp, B. C., Voorhout, W. F., Van Amerongen, A., Brunink, F., Batenburg, J. J. and Wir...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1994
ISSN: 0014-5793
DOI: 10.1016/0014-5793(94)00404-8